Structure of PDB 7m4v Chain E Binding Site BS01 |
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| >7m4v Chain A (length=2732)
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agucaaguaauuaagugcaugugguggaugccuuggcagucagaggcgau
gaaagacgugauagccugcgaaaagcuccggggaggcggcaaauauccuu
ugauccggagaugucugaaugggggaacccaccuacuuuaagguagguau
ugcaacaugaauacauaguguugcaaggcgaacgaggggaagugaaacau
cucaguacccuuaggaaaagaaaucaauugagauucccucaguagcggcg
agcgaacggggaucagcccauuaaguuauguguguuuuaguggaacgcuc
ugggaagugcgaacguagagggugauauucccguacacgaaagggcacac
auaaugaugacgaguagggcgaggcacgugaaaccuugucugaauauggg
gggaccauccuccaaggcuaaauacuccugacugaccgauagugaaccag
uaccgugagggaaaggcgaaaagaaccccugugaggggagugaaauagau
ccugaaaccgcaugcauacaagcagugggagcaccuucguggugugacug
cguaccuuuuguauaaugggucagcgacuuauauucaguagcgagguuaa
ccguauaggggagccguagagaaaucgagucuuaauagggcguuuaguug
cuggguauagacccgaaaccaggcgaucuauccaugagcagguugaaggu
uggguaacacuaacuggaggaccgaacccacugucguugaaaagccaggg
gaugacuuguggauaggggugaaaggcuaaucaagccuggugauagcugg
uucuccccgaaagcuauuuagguagcgccucggacgaauaccauaggggg
uagagcacuguuucggcaccgaugcaaacuccgaauaccuaugaguacua
uccgggagacagacugcgggugcuaacguccguagucaagaggaaaacaa
uccagaccgccagcuaaggccccaaaaucauaguuaagugggaaacgaug
ugggaaggcauagacagcuauagucgagucggccugcgcggaagauguaa
cggggcuaaaacuaugugccgaagcugcggauguauacuuuguauacgug
guaggggagcguucuguaagccgaugaagguguguugagaagcaugcugg
agguaucagaagugcgaaugcugacgugaguaacgacaaaacgggugaaa
aacccguucgccgaaagaccaaggguuccaguccaacguuaaucggggcu
gggugagucgaccccuaaggcgaggccgaaaggcguagucgaugggaaaa
ugguuaauauuccauuacuucuguguaaugcgaugagaggacggagaagg
cuaaaucagccuggcguugguuguccaggugaaaggauguaggcauguau
cuuaggcaaauccgggguacucuaugcugagaucugauagcaagcuguac
uugugcagcgaagugguugaugccaugcuuccaggaaaagucucuaagcu
ucaguuacacaggaaucguacccgaaaccgacacagguggucaggucgag
uagaccaaggcgcuugagagaacucugcugaaggaacuaggcaaaauggu
accguaacuucgggagaagguacgcuguuguuggugauggaacucgcuuc
cugagcugacgacagccgcagaaaccaggccgcugcaacuguuuauuaaa
aacauagcacucugcaaacacgaaaguggacguauagggugugaugccug
cccggugcuggaagguuaauugaugggguuagcguaagcgaagcucuuga
ucgaagccccaguaaacggcggccguaacuauaacgguccuaagguagcg
aaauuccuugucggguaaguuccgaccugcacgaauggcauaaugauggc
ggcgcugucuccagcagaggcucagugaaaucgaaaucgcugugaagaug
caguguacccgcggcuagacggaaagaccccgugaaccuuuacugcagcu
ugacacugaacuuugauugagguucuaacucugucccgugauccgggacg
aggaccgugucugguggguaguuugacuggggcggucuccuccuaaagag
uaacggaggaguacgaaggugcgcucagcguggucggaaaucacgcguag
aguauaaaggcaaaagcgcgcuuaacugcgagacccacaagucgagcagg
uacgaaaguaggucuuagugauccggugguucuguauggaagggccaucg
cucaacggauaaaagguacucuggggauaacaggcugauaccgcccaaga
guucauaucgacggcgguguuuggcaccucgaugucggcucaucucaucc
uggggcugaagcaggucccaaggguauggcuguucgccauuuaaagaggu
acgcgagcuggguuuagaacgucgugagacaguucggucccuaucuaccg
ugggcgcuggaaauuugagaggaucugcuccuaguacgagaggaccagag
uggacgaaccucugguguaccgguugugacgccagucgcaucgccgggua
gcuauguucggaagggauaaccgcugaaagcaucuaagcgggaagccuac
cucaagauaagauuucccuaggacuuuauguccucuaaagagccguucga
gacuaggacguugauagguuggauguggaagcauagugauaugugaagcu
gaccaauacuaauugcucgugaggcuugacua |
<<<<<<<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<...
...<<<<<<.[..(((.>>>.....<<<<<<<..<<.)))...]..>>..
...>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>
>......>>>>>.>.........<<....>>...<<<<<.....<<....
.>>....>>>>>...<<<...<..<<<<<<<<<<<<<<.<<<...<<<.<
......>.>>>((......<<<.....))>>>...>>>...>>>>>>>>>
>>>>>...>.......<<<<<<<<.........>>>>>>>>......<<<
<<..<<<<>>>>>..>>>......]].>>>>>>>.]].............
..<<....>>....]].........<<<<.....>>>>............
......>>>>>>>>>>>.......<<<<..<<<<<.....>>>>>..>>>
>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...
<<.....>>...>>>...<<....>>..<<<<.....>>>>.....>>>>
>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<
<<<......>>>>>>.....>>>...<<<.<<<.<........>.>>>>>
>....>>>>>>>>>...<<<.....>>>......>>>>>>...>..>.>>
..<<<<<<....<<<<<....>>>>>.<<<<<<<....<<<<<<<<<...
..<<<...<<<.<<<<..>>>>.>>>..>>.>.....>>>>>>.>>>...
>>>>>>.>...<<<<<<<<<<......>>>>>>>>>>....<<<......
>>>...<<<<.<<<...<<<(((.....<<<<<<...........<<..<
<<<<..<<........<<<..>>>....>>..>>>>>.>>..........
.)))......>>>>>>.>>>...>>>>>>><<<<<<<<...>>>>>>>>.
...>>>>>><.<<<<<...<<<......<<<<<<<<....>>>>>>>>..
.>>>..>>>>>..>.....>>>>>><......<<.....<<<<<<.....
..>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>
>>....((<<<.<<<...<<<...<<<....>>>...>>>...>>>..<<
<<<........>>>>>))<<<<<<<<<<<<<...<<<<....<<<<..<<
<..<<<<<<<<<<<...((((...>>>>>>....<<<<...<<<<.<<<<
<<..<<.....>>.>>>>>>....>>>>...>>>>........<<<<<..
....>>>>>....>>>>>...>>>...>>>>.........>>>>...>>.
...>>>>>>>>>>>.>>>..>>.....<<......>>>>>>>.<<<<...
..>>>>..>>>>..<<<<....<<<<<<<<.<<...............<<
<<<.....<..>......>>>>><<<<<<<<<<<<...<<<<.....>>>
>...>>>>>>>>>>>>............<<<<<<<<<..<<<........
.>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.<
<<..<<<<<<<..<<<<.......<<<<<<.<<....>>..>>>>>>...
....>>>>>>>>>..>>>>><<<<<<.......>>>>>>........<..
.........<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>>
>>>.....>>.>>>>>>>>.>>>>>>.....>.....<<<<<........
>>>>>..<<<<<<<.<<<<.[[......<<<<.[[<<<<..<<<<..<<<
.<<<<<.<<<<<<<<..>>>>>>>>...<<<.<<<<<<.....>>>>>>>
>>....>>>>>.>>>...>>>>..<<<<.....>>>><<<<<<.......
....>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>....
.<<.[.(((>>....>>>>>>>...<<<<..<<<......>>>..>>>>.
<<<....>>>.>>)))]......<<<<<<<.((..>>>>..))>>>>>>>
.............>>>>..]]>>>>.......<<<<...<<<<<<...<<
.......>>...>>>>>>....>>>.>.......<<<<<.<<<<<<..<<
<<<<<<<......>>>>>>..>>>.<<<<<.....>>>>>.....>>>>>
..>...>>>.>>....<<<<<<<....>>>.>>>>....]]..>>>>>>>
>>>>....<<<<<<<...<<<<..<<<<<<.................>>>
>>>.<<<<<...<<<<...<<<<<<<<<<<))))>>>>>>..>>>>>...
>>>>.>>>>>...<<<....<<<<<...........>>>>>....>>>.>
>>>.......>>>>>>>..<<<<<.....>>>>><....<<<<<<<<<..
.....>>>>>....<<<<<<<<..<<....<<<<<....>>>>>...>>.
..>>>>>.>>>...>>>>..>..>>>>>>>>. |
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| PDB | 7m4v Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii. |
| Resolution | 2.54 Å |
Binding residue
(original residue number in PDB) | H28 Q29 Y34 L35 R39 Q40 T42 R43 H45 K46 R48 A49 V51 S52 G53 K57 Q61 K62 G63 G65 R66 A67 R68 G70 R73 I76 W77 V78 G79 K82 T83 F84 Q89 K94 N96 K98 M99 Y100 P128 K129 T130 L158 R161 N162 P164 |
Binding residue
(residue number reindexed from 1) | H28 Q29 Y34 L35 R39 Q40 T42 R43 H45 K46 R48 A49 V51 S52 G53 K57 Q61 K62 G63 G65 R66 A67 R68 G70 R73 I76 W77 V78 G79 K82 T83 F84 Q89 K94 N96 K98 M99 Y100 P128 K129 T130 L158 R161 N162 P164 |
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| Enzyme Commision number |
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