Structure of PDB 7leu Chain E Binding Site BS01
Receptor Information
>7leu Chain E (length=423) Species:
10090
(Mus musculus) [
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NWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKF
VSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASP
HAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACG
YLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWA
ISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGT
DEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVV
NHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEP
LMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIE
ALQRHENESVYKASLNLIEKYFS
Ligand information
>7leu Chain B (length=8) Species:
9606
(Homo sapiens) [
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EEKRKRTY
Receptor-Ligand Complex Structure
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PDB
7leu
Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Resolution
2.82 Å
Binding residue
(original residue number in PDB)
S105 F138 W142 N146 S149 G150 T155 Q181 W184 N188 D192 N228 W231
Binding residue
(residue number reindexed from 1)
S31 F64 W68 N72 S75 G76 T81 Q107 W110 N114 D118 N154 W157
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7leu
,
PDBe:7leu
,
PDBj:7leu
PDBsum
7leu
PubMed
35260573
UniProt
P52293
|IMA1_MOUSE Importin subunit alpha-1 (Gene Name=Kpna2)
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