Structure of PDB 7kui Chain E Binding Site BS01

Receptor Information
>7kui Chain E (length=269) Species: 269446 (Rous sarcoma virus (strain Schmidt-Ruppin A)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLREAKDLHTALHIGPRALSKACNISMQQAREVVQTCPHCNSAPALEAGV
NPRGLGPLQIWQTDFTLEPRMAPRSWLAVTVDTASSAIVVTQHGRVTSVA
VQHHWATAIAVLGRPKAIKTDNGSCFTSKSTREWLARWGIAHTTGIPGNS
QGQAMVERANRLLKDKIRVLAEGDGFMKRIPTSKQGELLAKAMYALNHFE
RGENTKTPIQKHWRPTVLTEGPPVKIRIETGEWEKGWNVLVWGRGYAAVK
NRDTDKVIWVPSRKVKPDI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7kui Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		G49 V50 N51 P52 T143 T144 G145 I146 Q151 A154 M155 R158 L162 E203 R244 Y246
Binding residue
(residue number reindexed from 1)		G49 V50 N51 P52 T143 T144 G145 I146 Q151 A154 M155 R158 L162 E203 R244 Y246
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:7kui, PDBe:7kui, PDBj:7kui
PDBsum7kui
PubMed33712691
UniProtP03354|POL_RSVP Gag-Pol polyprotein (Gene Name=gag-pol)

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