Structure of PDB 7cyy Chain E Binding Site BS01

Receptor Information
>7cyy Chain E (length=492) Species: 1388,235909,1202714 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSLRPYEFWFVTGSQHLYGEEALKQVEEHSRIMVNEWNRFPFPFVFKSVV
TTPEEIRRVCLEANASEQCAGVVTWMHTFSPAKMWIGGLLELRKPLLHLH
TQFNRDIPWDSIDMDFMNLNQSAHGDREFGFMVTRLGMPRKVIVGHWQDA
EVARRVRGWAMTAVAAAVSRGLKVARFGDNMRQVAVTEGDKVEAEARFGW
SVNGYGVGDLAERVRAVSEAEIDRLIDEYQSLYEFAPGCEKGGPLHDGVR
EQARIELGLRSFLEEGGFEAFTTTFEDLHGMKQLPGLAVQRLMAEGYGFG
GEGDWKTAALVRLMKVMADGKGTSFMEDYTYHFEPGNEMILGAHMLEVCP
TIAATRPRIEVHPLSIGGKEDPARLVFDGGEGAAVNASLIDLGHRFRLIV
NEVDAVKPEHDMPKLPVARILWKPRPSLRDSAEAWILAGGAHHTCFSFAV
TTEQLQDFAEMAGIECVVINEHTSVSSFKNELKWNEVFWRGR
Ligand information
Ligand IDRB0
InChIInChI=1S/C5H12O5/c6-1-3(8)5(10)4(9)2-7/h3-10H,1-2H2/t3-,4+,5-
InChIKeyHEBKCHPVOIAQTA-ZXFHETKHSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C(C(C(CO)O)O)O)O
CACTVS 3.370OC[CH](O)[CH](O)[CH](O)CO
ACDLabs 12.01OC(CO)C(O)C(O)CO
OpenEye OEToolkits 1.7.6C([C@H](C([C@H](CO)O)O)O)O
CACTVS 3.370OC[C@H](O)[C@H](O)[C@H](O)CO
FormulaC5 H12 O5
NameD-ribitol
ChEMBLCHEMBL3137744
DrugBankDB14704
ZINCZINC000100014205
PDB chain7cyy Chain E Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7cyy Crystal structure of Arabinose isomerase from hyper thermophilic hybrid AI8 with Adonitol
Resolution2.6 Å
Binding residue
(original residue number in PDB)		F280 E307 E332 Y334 M350 H447
Binding residue
(residue number reindexed from 1)		F275 E302 E327 Y329 M345 H442
Annotation score1
Enzymatic activity
Enzyme Commision number 5.3.1.4: L-arabinose isomerase.
Gene Ontology
Molecular Function
GO:0008733 L-arabinose isomerase activity
GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses
Biological Process
GO:0005996 monosaccharide metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cyy, PDBe:7cyy, PDBj:7cyy
PDBsum7cyy
PubMed
UniProtK0IGW6;
Q2VMT2;
Q5KYP7|ARAA_GEOKA L-arabinose isomerase (Gene Name=araA)

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