Structure of PDB 7cro Chain E Binding Site BS01

Receptor Information
>7cro Chain E (length=98) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVKALQEASEAYLVGLFEDTNLCGIHAKRVTIKPKDIQLARRIRGER
Ligand information
>7cro Chain A (length=168) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcccgatcccctggagaatcccggtgccgaggccgctcaattggtcgtag
acagctctagcaccgcttaaacgcacgtacgcgctgtcccccgcgtttta
accgccaaggggattactccctagtctccaggcacgtgtcagatatatac
atcctgttccagtgccgg
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7cro Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.
Resolution3.75 Å
Binding residue
(original residue number in PDB)		R72 R83 F84 S86 V117 T118
Binding residue
(residue number reindexed from 1)		R36 R47 F48 S50 V81 T82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:7cro, PDBe:7cro, PDBj:7cro
PDBsum7cro
PubMed33361816
UniProtQ92133

[Back to BioLiP]