Structure of PDB 7cnv Chain E Binding Site BS01

Receptor Information
>7cnv Chain E (length=130) Species: 2224 (Methanothrix thermoacetophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIQQTGYSKKVMEHFMNPRNVGVIDDPDGYGKVGNPVCGDLMEIFIKVGD
EKIEDIKFRTFGCGAAIATSSMITEMARGKSLEEAMRITRNDVADALDGL
PPQKMCCSNLAADALHAAINDYLSKKQKHL
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7cnv Chain E Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7cnv [2Fe-2S] clusters-assembled dimeric structures of IscU iron-sulfur scaffold
Resolution2.23 Å
Binding residue
(original residue number in PDB)		C38 D40 C63 K104 C107
Binding residue
(residue number reindexed from 1)		C38 D40 C63 K104 C107
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0008198 ferrous iron binding
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006879 intracellular iron ion homeostasis
GO:0016226 iron-sulfur cluster assembly
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:7cnv, PDBe:7cnv, PDBj:7cnv
PDBsum7cnv
PubMed
UniProtA0B757

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