Structure of PDB 7cj8 Chain E Binding Site BS01

Receptor Information
>7cj8 Chain E (length=287) Species: 1727196 (Methylomonas sp. DH-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMAFPKRLEYGGHALVWSGDWSAAGARKAIAGAARAGYDYIEIALLDPWQ
IDVALTKDLLQEYNLRAHASLGLSAATDVTSTDPAIVAKGDELLRKATDV
LYALGGSELCGVIYCALGKYPGPASRENRANSVAAMQRLADYAADKGINI
DLEVVNRYETNIMNTGLEGLAFLDEVNRPNAFLHLDTYHMNIEENGMAKS
VLAAGDRLGYVHIGESHRGYLGTGNVDFASFFAALKQIDYRGPITFESFS
SEIVDPKLSNTLCVWRNLWHDSDDLAGKALEFIKQRY
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7cj8 Chain E Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7cj8 Crystal structure of a novel homodimeric l-ribulose 3-epimerase from Methylomonus sp.
Resolution2.05 Å
Binding residue
(original residue number in PDB)		E152 D185 H211 E246
Binding residue
(residue number reindexed from 1)		E153 D186 H212 E247
Annotation score1
Enzymatic activity
Enzyme Commision number 5.1.3.31: D-tagatose 3-epimerase.
Gene Ontology
Molecular Function
GO:0016853 isomerase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7cj8, PDBe:7cj8, PDBj:7cj8
PDBsum7cj8
PubMed33838083
UniProtA0A172U6X0|LR3E_METSD L-ribulose 3-epimerase (Gene Name=AYM39_05640)

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