Structure of PDB 7ccr Chain E Binding Site BS01

Receptor Information
>7ccr Chain E (length=98) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
Ligand information
>7ccr Chain I (length=147) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acaggatgtatatatctgacacgtgcctggagactagggagtaatcccct
tggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgcta
gagctgtctacgaccaattgagcggcctcggcaccgggattctccag
Receptor-Ligand Complex Structure
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PDB7ccr Structural basis for nucleosome-mediated inhibition of cGAS activity.
Resolution4.9 Å
Binding residue
(original residue number in PDB)		H39 R40 Y41 R42 P43 V46 R49 K56 R63 K64 L65 R69
Binding residue
(residue number reindexed from 1)		H2 R3 Y4 R5 P6 V9 R12 K19 R26 K27 L28 R32
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:7ccr, PDBe:7ccr, PDBj:7ccr
PDBsum7ccr
PubMed33051594
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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