Structure of PDB 7bzi Chain E Binding Site BS01

Receptor Information
>7bzi Chain E (length=359) Species: 77133 (uncultured bacterium) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSTGIAPKRYVYYPGSEELGPDEIRVIACGTGMPTARRAQAAAAWVVELG
NGDKFIVDIGSGSMANIQSLMIPANYLTKIFLTALHTDHWGDLVSMWAGG
WTAGRTDPLEVWGPSGSREDMGTKYAVEHMLKAYNWDYMTRAVTINPRPG
DINVHEFDYRALNEVVYQENGVTFRSWPCIHAGDGPVSFALEWNGYKVVF
GGDTAPNIWYPEYAKGADLAIHECWMTSDQMMTKYNQPAQLALRINLDFH
TSAQSFGQIMNMVQPRHAVAYHFFNDDDTRYDIYTGVRENYAGPLSMATD
MMVWNITRDAVTERMAVSPDHAWDVAGPRNRASEYTQYILDGRLNVDEAN
AHWKQEFMG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7bzi Chain E Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7bzi Structural Study of Metal Binding and Coordination in Ancient Metallo-beta-Lactamase PNGM-1 Variants.
Resolution1.94 Å
Binding residue
(original residue number in PDB)		H96 D210 H279
Binding residue
(residue number reindexed from 1)		H89 D203 H272
Annotation score1
Enzymatic activity
Enzyme Commision number 3.5.2.6: beta-lactamase.
Gene Ontology
Molecular Function
GO:0008800 beta-lactamase activity
GO:0016787 hydrolase activity
GO:0042781 3'-tRNA processing endoribonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0042780 tRNA 3'-end processing

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Molecular Function
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Biological Process
External links
PDB RCSB:7bzi, PDBe:7bzi, PDBj:7bzi
PDBsum7bzi
PubMed32664695
UniProtA0A2U8UYM6

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