Structure of PDB 7bai Chain E Binding Site BS01
Receptor Information
>7bai Chain E (length=119) Species:
9606
(Homo sapiens) [
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KENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQ
FSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQ
TLYSKWKDFHFEKIPFDPA
Ligand information
>7bai Chain V (length=12) [
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gacgcuagcguc
............
Receptor-Ligand Complex Structure
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PDB
7bai
A conserved isoleucine in the RNA sensor RIG-I controls immune tolerance to mitochondrial RNA
Resolution
3.4 Å
Binding residue
(original residue number in PDB)
C829 H830 F853 K858 K861 G874 K888 K907 K909
Binding residue
(residue number reindexed from 1)
C27 H28 F51 K56 K59 G72 K86 K105 K107
Enzymatic activity
Enzyme Commision number
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:7bai
,
PDBe:7bai
,
PDBj:7bai
PDBsum
7bai
PubMed
UniProt
O95786
|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)
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