Structure of PDB 6yhs Chain E Binding Site BS01

Receptor Information
>6yhs Chain E (length=175) Species: 575584 (Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRVAKAPVTVPNGVTVTQNGRQVEVKGSKGTLSFNLHALVELKQEEGKLQ
LAPAKESKDAWMQAGTARAVLNNLVKGVSEGFERKLQLVGVGYKAAVKGT
VVNLNLGYSHPIDYALPEGVTAETPTATEIILKSANKQLLGQVAAEIRAY
RSPEPYKGKGVRYSDEVILRKEAKK
Ligand information
>6yhs Chain 1 (length=2672) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucaaguaauuaagugcaugugguggaugccuuggcagucagaggcgaug
aaagacgugauagccugcgaaaagcuccggggaggcggcaaauauccuuu
gauccggagaugucugaaugggggaacccaccuacuuuaagguagguauu
gcaacaugaauacauaguguugcaaggcgaacgaggggaagugaaacauc
ucaguacccuuaggaaaagaaaucaauugagauucccucaguagcggcga
gcgaacggggaucagcccauuaaguuauguguguuuuaguggaacgcucu
gggaagugcgaacguagagggugauauucccguacacgaaagggcacaca
uaaugaugacgaguagggcgaggcacgugaaaccuugucugaauaugggg
ggaccauccuccaaggcuaaauacuccugacugaccgauagugaaccagu
accgugagggaaaggcgaaaagaaccccugugaggggagugaaauagauc
cugaaaccgcaugcauacaagcagugggagcaccuuuguggugugacugc
guaccuuuuguauaaugggucagcgacuuauauucaguagcgagguuaac
cguauaggggagccguagagaaaucgagucuuaauagggcguuuaguugc
uggguauagacccgaaaccaggcgaucuauccaugagcagguugaagguu
ggguaacacuaacuggaggaccgaacccacugucguugaaaagccagggg
augacuuguggauaggggugaaaggcuaaucaagccuggugauagcuggu
ucuccccgaaagcuauuuagguagcgccucggacgaauaccauagggggu
agagcacuguuucggcuaaccgaugcaaacuccgaauaccuaugaguacu
auccgggagacagacugcgggugcuaacguccguagucaagaggaaaaca
auccagaccgccagcuaaggccccaaaaucauaguuaagugggaaacgau
gugggaaggcaagucggccugcgcggaagauguaacggggcuaaaacuau
gugccgaagcugcggauguauacuuuguauacgugguaggggagcguucu
guaagccgaugaagguguguugagaagcaugcuggagguaucagaagugc
gaaugcugacgugaguaacgacaaaacgggugaaaaacccguucgccgaa
agaccaaggguuccaguccaacguuaaucggggcugggugagucgacccc
uaaggcgaggccgaaaggcguagucgaugggaaaaugguuaauauuccau
uacuucuguguaaugcgaugagaggacggagaaggcuaaaucagccuggc
guugguuguccaggugaaaggauguaggcauguaucuuaggcaaauccgg
gguacucuaugcugagaucugaaagugguugaugccaugcuuccaggaaa
agucucuaagcuucaguuacacaggaaucguacccgaaaccgacacaggu
ggucaggucgaguagaccaaggcgcuugagagaacucugcugaaggaacu
aggcaaaaugguaccguaacuucgggagaagguacgcuguuguuggugau
ugagcugacgacagccgcagaaaccaggccgcugcaacuguuuauuaaaa
acauagcacucugcaaacacgaaaguggacguauagggugugaugccugc
ccggugcuggaagguuaauugaugggguuagcguaagcgaagcucuugau
cgaagccccaguaaacggcggccguaacuauaacgguccuaagguagcga
aauuccuugucggguaaguuccgaccugcacgaauggcauaaugauggcg
gcgcugucuccagcagaggcucagugaaaucgaaaucgcugugaagaugc
aguguacccgcggcuagacggaaagaccccgugaaccuuuacugcagcuu
gacacugaacugguucuaacucugucccgugauccgggacgaggaccgug
ucugguggguaguuugacuggggcggucuccuccuaaagaguaacggagg
aguacgaaggugcgcucagcguggucggaaaucacgcguagaguauaaag
gcaaaagcgcgcuuaacugcgagacccacaagucgagcagguacgaaagu
aggucuuagugauccggugguucuguauggaagggccaucgcucaacgga
uaaaagguacucuggggauaacaggcugauaccgcccaagaguucauauc
gacggcgguguuuggcaccucgaugucggcucaucucauccuggggcuga
agcaggucccaaggguauggcuguucgccauuuaaagagguacgcgagcu
ggguuuagaacgucgugagacaguucggucccuaucuaccgugggcgcug
gaaauuugagaggaucugcuccuaguacgagaggaccagaguggacgaac
cucugguguaccgguugugacgccagucgcaucgccggguagcuauguuc
ggaagggauaaccgcugaaagcaucuaagcgggaagccuaccucaagaua
agauuucccuaggacuuuauguccucuaaagagccguucgagacuaggac
guugauagguuggauguggaagcauagugauaugugaagcugaccaauac
uaauugcucgugaggcuugacu
<<<<<<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<....
..<<<<<<....(((.>>>.....<<<<<<<..<<.)))......>>...
..>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<<
<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>>
......>>>>>.>.........<<....>>...<<<<<.....<<.....
>>....>>>>>...<<<......<<<<<<<<<<<<<<.<<<...<<<.<.
.....>.>>>((......<<<.....))>>>...>>>...>>>>>>>>>>
>>>>...........<<<<<<<<.........>>>>>>>>......<<<<
<..<<<<>>>>>..>>>......]].>>>>>>>.]]..............
.<<....>>....]].........<<<<.....>>>>.............
.....>>>>>>>>>>>.......<<<<..<<<<<.....>>>>>..>>>>
...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<
<.....>>...>>>...<<....>>..<<<<.....>>>>.....>>>>>
>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<<...<<<<
<<......>>>>>>.>...>>>...<<<.<<<.<........>.>>>>>>
....>>>>>>>>>...<<<.....>>>......>>>>>>...>..>.>>.
.<<<<<<....<<<<<....>>>>>.<<<<<<<....<<<<<<<<<....
.<<<...<<<.<<<<....>>>>.>>>..>>.>.....>>>>>>.>>>..
.>>>>>>.>...<<<<<<<<<<......>>>>>>>>>>....<<<.....
.>>>...<<<<.<<<...<<<(((.....<<<<<<...........<<..
<<<<<..<<....>>..>>>>>.>>...........)))......>>>>>
>.>>>...>>>>>>><<<<<<<<...>>>>>>>>....>>>>>><.<<<<
<...<<<......<<<<<<<<....>>>>>>>>...>>>..>>>>>..>.
....>>>>>><......<<.....<<<<<<.......>>>>>><<<<...
.<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<.<<<
...<<<...<<<....>>>...>>>...>>>..<<<<<........>>>>
>))<<<<<<<<<<<<<...<<<<....<<<<..<<<..<<<<<<<<<<<.
..((((...>>>>>>....<<<<...<<<<.<<<<<<..<<.....>>.>
>>>>>....>>>>...>>>>.....>>>>>...>>>...>>>.>......
..>>>>...>>....>>>>>>>>>>>.>>>..>>.....<<......>>>
>>>>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<.....
....<.....<<<<<....<<..>>.....>>>>><<<<<<<<<<<<...
...>>>>>>>>>>>>............<<<<<<<<<..<<<.........
>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.<<
<..<<<<<<<..<<<<.......<<<<<..<<....>>...>>>>>....
...>>>>>>>>>..>>>>><<<<<<.......>>>>>>........<...
........<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>>>
>>..>..>>.>>>>>>>>.>>>>>>.....>.....<<<<<........>
>>>>..<<<<<<<.<<<<.[[......<<<<.[[<<<<..<<<<..<<<.
<<<<<.<<<<..>>>>...<<<.<<<<<<.....>>>>>>>>>....>>>
>>.>>>...>>>>..<<<<.....>>>><<<<<<...........>>>>>
>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<<.[.(((
>>....>>>>>>>...<<<<..<<<......>>>..>>>>.<<<....>>
>.>>)))]......<<<<<<<.((..>>>>..))>>>>>>>.........
....>>>>..]]>>>>.......<<<<...<<<<<<...<<.......>>
...>>>>>>....>>>.>.......<<<<<.<<<<<<..<<<<<<<<<..
....>>>>>>>..>>.<<<<<.....>>>>>.....>>>>>..>...>>>
.>>....<<<<<<<....>>>.>>>>....]]..>>>>>>>>>>>....<
<<<<<<...<<<<..<<<<<<.................>>>>>>.<<<<<
...<<<<...<<<<<<<<<<<))))>>>>>>..>>>>>...>>>>.>>>>
>...<<<....<<<<<...........>>>>>....>>>.>>>>......
.>>>>>>>..<<<<<.....>>>>><....<<<<<<<<<.......>>>>
>....<<<<<<<<..<<....<<<<<....>>>>>...>>...>>>>>.>
>>...>>>>..>..>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6yhs Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		S2 R3 K59 M63 Q64 G66 T67 S110 H111 Q139 G142 Q143 Y157 K158 K160 K172 A174
Binding residue
(residue number reindexed from 1)		S1 R2 K58 M62 Q63 G65 T66 S109 H110 Q138 G141 Q142 Y156 K157 K159 K171 A173
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6yhs, PDBe:6yhs, PDBj:6yhs
PDBsum6yhs
PubMed32857965
UniProtD0CD12

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