Structure of PDB 6xp6 Chain E Binding Site BS01

Receptor Information
>6xp6 Chain E (length=180) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTL
LGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTIS
PSNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVM
LEMTPQRGDVYTCHVEHPSLQSPITVEWRA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6xp6 A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		F11 S28 P56 A57 W61 R70 K71 R77 V78 H81 N82 L85
Binding residue
(residue number reindexed from 1)		F9 S26 P54 A55 W59 R68 K69 R75 V76 H79 N80 L83
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:6xp6, PDBe:6xp6, PDBj:6xp6
PDBsum6xp6
PubMed34417258
UniProtQ5Y7D3

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