Structure of PDB 6w7n Chain E Binding Site BS01

Receptor Information
>6w7n Chain E (length=150) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNGRVGFGYGKAREVPAA
IQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEGTGIIAGG
AMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGK
Ligand information
>6w7n Chain A (length=1372) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaauugaagaguuugaucauggcucagauugaacgcuggcggcaggccua
acacaugcaagucgaacgguaacaggaagaagcuugcuucuuugcugacg
aguggcggacgggugaguaaugucugggaaacugccugauggagggggau
aacuacuggaaacgguagcuaauaccgcauaacgucgcaagaccaaagag
ggggaccuucgggccucuugccaucggaugugcccagaugggauuagcua
guaggugggguaacggcucaccuaggcgacgaucccuagcuggucugaga
ggaugaccagccacacuggaacugagacacgguccagacuccuacgggag
gcagcaguggggaauauugcacaaugggcgcaagccugaugcagccaugc
cgcguguaugaagaaggccuucggguuguaaaguacuuucagcggggagg
aagggaguaaaguuaauaccuuugcucauugacguuacccgcagaagaag
caccggcuaacuccgugccagcagccgcgguaauacggagggugcaagcg
uuaaucggaauuacugggcguaaagcgcacgcaggcgguuuguuaaguca
gaugugaaauccccgggcucaaccugggaacugcaucugauacuggcaag
cuugagucucguagagggggguagaauucgaggaauaccgguggcgaagg
cggcccccuggacgaagacugacgcucaggugcgaaagcguggggagcaa
aguaguccacgccguaaacgaugucgacuuggagguugugcccuugaggc
guggcuuccggagcuaacgcguuaagucgaccgccuggggaguacggccg
caagguuaaaacucaaaugaauugacgggggcccgcacaagcgguggagc
augugguuuaauucgaugcaacgcgaagaaccuuaccuggucuugacauc
cacggaaguuuucagagaugagaaugugccuucgggaaccgugagacagg
ugcugcauggcugucgucagcucguguugugaaauguuggguuaaguccc
gcaacgagcgcaacccuuauccuuuguugccagcgguccggccgggaacu
caaaggagacugccagugauaaacuggaggaagguggggaugacgucaag
ucaucauggcccuuacgaccagggcuacacacgugcuacaauggcgcaua
caaagagaagcgaccucgcgagagcaagcggaccucauaaagugcgucgu
aguccggauuggagucugcaacucgacuccaugaagucggaaucgcuagu
aaucguggaucagaaugccacggugaauacguucccgggccuuguacaaa
ccguaggggaaccugcgguugg
........<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<....
.<<<.<<<..<<<..<<.<<..<<<<<<<<........>>>>>.>>>>>.
.>>>>>......<<.......<<<<<<<..<<...<<<<<<<.<.<<...
..<<<<<......>>>>>......>>.>.....<<<....>>>....<<<
<<.<.<<....>>>>>>>>.>>>>>>>..>>.>>>>>>><<<....<<<.
.<<<<<<<.........>>>>>>>>>>......>>>..<<<<<<<<....
>>>>...>>>>.>>.<<<<.<<.........>>>>>>.<<<<<..>>>>>
...>>>>>>.........<<<....<<<<....>>>>..>>>..>>.>>>
>>>..<<<<......<<<......>>>.....>>>>...<.<<<<<....
..<.<<<<<<.<.......>.>>>>>>.>........>>>>>....>..<
<<<<(((...<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>
>>>>>>..........<<<((.....<<<<...<<<.<<<<<<<.<<<<<
<<<<<......<<<<<<.....>>>>>>....>>>>>>>>..>>>>>>>>
>...<<<<<<<<...<<<<<<<....<<..>>...........<<....>
>.>>>>>>>..>>>>.>>>>...>>>...>>>>....<<<<<<...<<..
....>>>>>>>>..........<<<<<<..<<<<<<<<<<<<.....>>>
>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<......<<<<.
...>>>>....>>>..)))).]<<<<<.<<<<<<<.<<.<<<<<<..<<<
<<<<<<<......<<........>>..........<<<<<<<......<<
<<<<<..<<<<<<<....>>>>>>>...<<....>>..>>>>>.>>.<<<
.<<<..<<<<<<<......<<<<<<<<<....>>>..<<<<......>>>
>..>>>>>>.....<<<<.<<<<<<<...<<..<<<.....>>>>>....
>>>>>>>.....<<<<<.....>>>>>........>>>>.......>.>>
>...>>>>>>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.
....<<<..<<...<<<....>>>...>>....>>>.....>>>>>>>..
....<....<<<<<<<........>>>>>>>....>.....>>>>>>...
.<<<<<<<.........>>>>>>>......>>...>>>>>>>>>>.>><<
<<<<<<<....>>>>>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6w7n Alternative conformations and motions adopted by 30S ribosomal subunits visualized by cryo-electron microscopy.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		V20 S21 T23 V24 Y49 K51 R53 K61 R68 T89 F94 S99 A106 G107 A124 K125 A126 Y127 S129 T130 N131
Binding residue
(residue number reindexed from 1)		V12 S13 T15 V16 Y41 K43 R45 K53 R60 T81 F86 S91 A98 G99 A116 K117 A118 Y119 S121 T122 N123
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0046677 response to antibiotic
GO:1990145 maintenance of translational fidelity
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6w7n, PDBe:6w7n, PDBj:6w7n
PDBsum6w7n
PubMed32989043
UniProtP0A7W1|RS5_ECOLI Small ribosomal subunit protein uS5 (Gene Name=rpsE)

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