Structure of PDB 6vyp Chain E Binding Site BS01

Receptor Information
>6vyp Chain E (length=110) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARTMQTARKSTGGKAPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVR
EIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPK
DIQLARRIRG
Ligand information
>6vyp Chain I (length=191) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcgaccctatacgcggccgccctggagaatcccggtgccgaggccgctc
aattggtcgtagacagctctagcaccgcttaaacgcacgtacgcgctgtc
ccccgcgttttaaccgccaaggggattactccctagtctccaggcacgtg
tcagatatatacatcctgtgcatgtattgaacagcgacgat
Receptor-Ligand Complex Structure
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PDB6vyp Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate.
Resolution4.99 Å
Binding residue
(original residue number in PDB)
A15 H39 Y41 G44 V46 R49 K64 L65 P66 R69 R83
Binding residue
(residue number reindexed from 1)
A15 H17 Y19 G22 V24 R27 K42 L43 P44 R47 R61
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:6vyp, PDBe:6vyp, PDBj:6vyp
PDBsum6vyp
PubMed32396821
UniProtP84233|H32_XENLA Histone H3.2

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