Structure of PDB 6ult Chain E Binding Site BS01
Receptor Information
>6ult Chain E (length=109) Species:
9606
(Homo sapiens) [
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SSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMD
LSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDV
FEFRYAKMP
Ligand information
>6ult Chain J (length=10) Species:
32630
(synthetic construct) [
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WKGYLCLRKR
Receptor-Ligand Complex Structure
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PDB
6ult
Cyclic peptides can engage a single binding pocket through highly divergent modes.
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
W370 P371 V376 L381 H433 D434 M438
Binding residue
(residue number reindexed from 1)
W25 P26 V31 L36 H88 D89 M93
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6ult
,
PDBe:6ult
,
PDBj:6ult
PDBsum
6ult
PubMed
33046654
UniProt
P25440
|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)
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