Structure of PDB 6ryu Chain E Binding Site BS01

Receptor Information
>6ryu Chain E (length=97) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSA
VMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
Ligand information
>6ryu Chain I (length=149) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcagaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaaggg
gattactccctagtctccaggcacgtgtcagatatatacatcgataggc
Receptor-Ligand Complex Structure
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PDB6ryu Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations.
Resolution4.0 Å
Binding residue
(original residue number in PDB)
R40 Y41 P43 G44 V46 R49 K64 L65 P66 R69 R83
Binding residue
(residue number reindexed from 1)
R2 Y3 P5 G6 V8 R11 K26 L27 P28 R31 R45
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:6ryu, PDBe:6ryu, PDBj:6ryu
PDBsum6ryu
PubMed32543371
UniProtP84233|H32_XENLA Histone H3.2

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