Structure of PDB 6p7n Chain E Binding Site BS01 |
| >6p7n Chain E (length=1070) Species: 1410628 (Lachnospiraceae bacterium ND2006)
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MSKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGV
KKLLDRYYLSFINDVLHSIKLKNLNNYISLFRNKELENLEINLRKEIAKA
FKGNEGYKSLFKKDIIETILPEFLDDKDEIALVNSFNGFTTAFTGFFDNR
ENMFSEEAKSTSIAFRCINENLTRYISNMDIFEKVDAIFDKHEVQEIKEK
ILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTEKIKGLNEYINL
YNQKTKQKLPKFKPLYKQGYTSDEEVLEVFRNTLNKNSEIFSSIKKLEKL
FKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKKK
AVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDE
IYKVYGSSEKLFDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFF
GEGKETNRDESFYGDFVLAYDILLKVDHIYDAIRNYVTQKPYSKDKFKLY
FQNPQFMGGWYRATILRYGSKYYLAIMDKGNYEKIFESASKKEVDKLVEE
GKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFM
RRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYEL
HIPIAINKCPKNIFKINTEVRVLLKHDDNPYVIGIDRGERNLLYIVVVDG
KGNIVEQYSLNEIINNFNGIRIKTDYHSLLDKKEKERFEARQNWTSIENI
KELKAGYISQVVHKICELVEKYDAVIALEDLNSGFKNSRVKVEKQVYQKF
EKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFIFYI
PAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFA
LDYKNFSRTDADYIKKWKLYSYGNRIRIDWEEVCLTSAYKELFNKYGINY
QQGDIRALLCEQSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKN
SDGIFYDSRNYEAQENAILPKNADANGAYNIARKVLWAIGQFKKAEDEKL
DKVKIAISNKEWLEYAQTSV |
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| PDB | 6p7n Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a. |
| Resolution | 4.9 Å |
Binding residue
(original residue number in PDB) | S14 K15 T16 R18 F19 K20 N157 K520 N706 K707 S710 K712 H714 G715 T716 N718 L719 H720 F745 R747 I765 N767 K768 N769 N772 K774 T777 L779 Y781 Y784 K787 R788 Q793 H797 N861 N862 F863 I868 L875 E898 S905 Q906 H909 K953 K960 |
Binding residue
(residue number reindexed from 1) | S14 K15 T16 R18 F19 K20 N149 K496 N560 K561 S564 K566 H568 G569 T570 N572 L573 H574 F599 R601 I619 N621 K622 N623 N626 K628 T631 L633 Y635 Y638 K641 R642 Q647 H651 N715 N716 F717 I722 L729 E752 S759 Q760 H763 K807 K814 |
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| Enzyme Commision number |
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