Structure of PDB 6m4h Chain E Binding Site BS01

Receptor Information
>6m4h Chain E (length=74) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNL
CAIHAKRVTIMPKDIQLARRIRGE
Ligand information
>6m4h Chain I (length=103) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gtgcctggagactagggagtaatccccttggcggttaaaacgcgggggac
agcgcgtacgtgcgtttaagcggtgctagagctgtctacgaccaattgag
cgg
Receptor-Ligand Complex Structure
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PDB6m4h Structural basis of nucleosome dynamics modulation by histone variants H2A.B and H2A.Z.2.2.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		R63 R72 R83 F84 R116 V117 T118 M120
Binding residue
(residue number reindexed from 1)		R4 R13 R24 F25 R57 V58 T59 M61
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0045296 cadherin binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0010467 gene expression
GO:0032200 telomere organization
GO:0040029 epigenetic regulation of gene expression
Cellular Component
GO:0000786 nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0016020 membrane
GO:0032991 protein-containing complex
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6m4h, PDBe:6m4h, PDBj:6m4h
PDBsum6m4h
PubMed33073403
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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