Structure of PDB 6lp5 Chain E Binding Site BS01

Receptor Information
>6lp5 Chain E (length=170) Species: 98310 (Sinonovacula constricta) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AETMPRQNFHQDSEAGINKQINMELYASYVYQSMSFYFDRDDVALKGFAK
FFKESSDEEREHAEKLMKYQNKRGGRIVLQPISKPDRDEWGSGLDAMKAA
LNLEKSVNQSLLELHKVADSHGDAQMCDFLEGEYLEEQVEAIKDLSDRIT
NLNRVGKGLGEWHYDQKLLS
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain6lp5 Chain E Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6lp5 Crystallographic characterization of ferritin from Sinonovacula constricta.
Resolution1.98 Å
Binding residue
(original residue number in PDB)		E25 E60 H63
Binding residue
(residue number reindexed from 1)		E24 E59 H62
Annotation score5
Enzymatic activity
Enzyme Commision number 1.16.3.1: ferroxidase.
Gene Ontology
Molecular Function
GO:0004322 ferroxidase activity
GO:0008198 ferrous iron binding
GO:0008199 ferric iron binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
GO:0006880 intracellular sequestering of iron ion
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:6lp5, PDBe:6lp5, PDBj:6lp5
PDBsum6lp5
PubMed31983429
UniProtD2JIV0

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