Structure of PDB 6j50 Chain E Binding Site BS01

Receptor Information
>6j50 Chain E (length=213) Species: 644223 (Komagataella phaffii GS115) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDNNRIISRLWRSFRTVKEMAADRGYFISQEEMDQSLEEFRSKICDSMGN
PQRKLMSFLANPTPEALEKYSDLGTLWVEFCDEPSVGIKTMRNFCLRIQE
KNFSTGIFIYQNNITPSANKMIPTVSPAIIETFQESDLVVNITHHELVPK
HIRLSDGEKSQLLQRYKLKESQLPRIQREDPVARYLGLKRGQVVKIIRRS
ETSGRYASYRICL
Ligand information
>6j50 Chain N (length=123) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tctcgtgcctggtgtctttaatccccttggcggttaaaacgcgggggaca
gcgcgtacgtgcgtttaagcggtgctagagctgtctacgaccaattgagc
ggcctcggcaccgggattctgat
Receptor-Ligand Complex Structure
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PDB6j50 Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Resolution4.7 Å
Binding residue
(original residue number in PDB)		T116 S118
Binding residue
(residue number reindexed from 1)		T115 S117
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001054 RNA polymerase I activity
GO:0001055 RNA polymerase II activity
GO:0001056 RNA polymerase III activity
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0006360 transcription by RNA polymerase I
GO:0006361 transcription initiation at RNA polymerase I promoter
GO:0006362 transcription elongation by RNA polymerase I
GO:0006363 termination of RNA polymerase I transcription
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation at RNA polymerase II promoter
GO:0006368 transcription elongation by RNA polymerase II
GO:0006383 transcription by RNA polymerase III
GO:0006384 transcription initiation at RNA polymerase III promoter
GO:0006386 termination of RNA polymerase III transcription
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
GO:0042797 tRNA transcription by RNA polymerase III
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005665 RNA polymerase II, core complex
GO:0005666 RNA polymerase III complex
GO:0005736 RNA polymerase I complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6j50, PDBe:6j50, PDBj:6j50
PDBsum6j50
PubMed30733384
UniProtC4R3P8

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