Structure of PDB 6i7a Chain E Binding Site BS01

Receptor Information
>6i7a Chain E (length=138) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDE
ESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQG
KDWGFKKFIRRNFLLDEANGLLPDDKLTLFCEVSVVQD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6i7a Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
Resolution2.2 Å
Binding residue
(original residue number in PDB)
Y87 Y123 K129 D130 W131 G132 F133 K134
Binding residue
(residue number reindexed from 1)
Y59 Y95 K101 D102 W103 G104 F105 K106
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6i7a, PDBe:6i7a, PDBj:6i7a
PDBsum6i7a
PubMed31026449
UniProtO43791|SPOP_HUMAN Speckle-type POZ protein (Gene Name=SPOP)

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