Structure of PDB 6esh Chain E Binding Site BS01

Receptor Information
>6esh Chain E (length=95) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSA
VMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGE
Ligand information
>6esh Chain I (length=137) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tatatctgacacgtgcctggagactagggagtaatccccttggcggttaa
aacgcgggggacagcgcgtacgtgcgtttaagcggtgctagagctgtcta
cgaccaattgagcggcctcggcaccgggattctccag
Receptor-Ligand Complex Structure
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PDB6esh Histone octamer rearranges to adapt to DNA unwrapping.
Resolution5.1 Å
Binding residue
(original residue number in PDB)
R40 Y41 V46 A47 R63 K64 L65 R69 R83
Binding residue
(residue number reindexed from 1)
R2 Y3 V8 A9 R25 K26 L27 R31 R45
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:6esh, PDBe:6esh, PDBj:6esh
PDBsum6esh
PubMed29323273
UniProtP84233|H32_XENLA Histone H3.2

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