Structure of PDB 6esg Chain E Binding Site BS01

Receptor Information
>6esg Chain E (length=92) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMA
LQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGE
Ligand information
>6esg Chain I (length=141) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tgtatatatctgacacgtgcctggagactagggagtaatccccttggcgg
ttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgctagagctg
tctacgaccaattgagcggcctcggcaccgggattctccag
Receptor-Ligand Complex Structure
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PDB6esg Histone octamer rearranges to adapt to DNA unwrapping.
Resolution5.4 Å
Binding residue
(original residue number in PDB)
P43 G44 R63 K64 P66 R83 K115
Binding residue
(residue number reindexed from 1)
P2 G3 R22 K23 P25 R42 K74
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:6esg, PDBe:6esg, PDBj:6esg
PDBsum6esg
PubMed29323273
UniProtP84233|H32_XENLA Histone H3.2

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