Structure of PDB 6dt1 Chain E Binding Site BS01

Receptor Information
>6dt1 Chain E (length=459) Species: 10665 (Tequatrovirus T4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MILKILNEIASIGSTKQKQAILEKNKDNELLKRVYRLTYSRGLQYYIKKW
PKPGIATQSFGMLTLTDMLDFIEFTLATRKLTGNAAIEELTGYITDGKKD
DVEVLRRVMMRDLECGASVSIANKVWPGLIPEQPQMLASSYDEKGINKNI
KFPAFAQLKADGARCFAEVRGDELDDVRLLSRAGNEYLGLDLLKEELIKM
TAEARQIHPEGVLIDGELVYHVAESRTASNGIANKSLKGTISEKEAQCMK
FQVWDYVPLVEIYSLPAFRLKYDVRFSKLEQMTSGYDKVILIENQVVNNL
DEAKVIYKKYIDQGLEGIILKNIDGLWENARSKNLYKFKEVIDVDLKIVG
IYPHRKDPTKAGGFILESECGKIKVNAGSGLKDKAGVKSHELDRTRIMEN
QNYYIGKILECECNGWLKSDGRTDYVKLFLPIAIRLREDKTKANTFEDVF
GDFHEVTGL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6dt1 T4 DNA ligase structure reveals a prototypical ATP-dependent ligase with a unique mode of sliding clamp interaction.
Resolution2.75 Å
Binding residue
(original residue number in PDB)		Q44 Y46 K48 K49 R164 S181 A183 N185 F457
Binding residue
(residue number reindexed from 1)		Q44 Y46 K48 K49 R164 S181 A183 N185 F429
Enzymatic activity
Enzyme Commision number 6.5.1.1: DNA ligase (ATP).
Gene Ontology
Molecular Function
GO:0003909 DNA ligase activity
GO:0003910 DNA ligase (ATP) activity
GO:0005524 ATP binding
GO:0016491 oxidoreductase activity
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6dt1, PDBe:6dt1, PDBj:6dt1
PDBsum6dt1
PubMed30169742
UniProtP00970|DNLI_BPT4 DNA ligase (Gene Name=30)

[Back to BioLiP]