Structure of PDB 6b46 Chain E Binding Site BS01

Receptor Information
>6b46 Chain E (length=334) Species: 208963 (Pseudomonas aeruginosa UCBPP-PA14) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ILSTASVLAFERKLDPSDALMSAGAWAQRDASQEWPAVTVREKSVRGTIS
NRLKTKDRDPAKLDASIQSPNLQTVDVANLPSDADTLKVRFTLRVLGGAG
TPSACNDAAYRDKLLQTVATYVNDQGFAELARRYAHNLANARFLWRNRVG
AEAVEVRINHIRQGEVARAWRFDALAIGLRDFKADAELDALAELIASGLS
GSGHVLLEVVAFARIGDGQEVFPSQELILDKGDKKGQKSKTLYSVRDAAA
IHSQKIGNALRTIDTWYPDEDGLGPIAVEPYGSVTSQGKAYRQPKQKLDF
YTLLDNWVLRDEAPAVEQQHYVIANLIRGGVFGE
Ligand information
>6b46 Chain M (length=60) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cuaagaaauucacggcgggcuugauguccgcgucuaccugguucacugcc
guguaggcag
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Receptor-Ligand Complex Structure
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PDB6b46 Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		F14 E15 R16 V49 R50 L76 W149 R150 Q229 L231 H256 Q258 K259 N262 R265 S290 G334 V335
Binding residue
(residue number reindexed from 1)		F10 E11 R12 V45 R46 L72 W145 R146 Q225 L227 H252 Q254 K255 N258 R261 S286 G330 V331
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6b46, PDBe:6b46, PDBj:6b46
PDBsum6b46
PubMed28985564
UniProtQ02MM1|CSY3_PSEAB CRISPR-associated protein Csy3 (Gene Name=csy3)

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