Structure of PDB 5yxu Chain E Binding Site BS01

Receptor Information
>5yxu Chain E (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWEA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5yxu an affinity enhanced T cell receptor in complex with HLA-A0201 restricted HCV NS3 peptide KLVALGINAV
Resolution2.7 Å
Binding residue
(original residue number in PDB)
M6 Y8 E64 K67 V68 H71 T74 D78 R98 Y100 T144 K147 W148 V153 Q156 Y160 W168 Y172
Binding residue
(residue number reindexed from 1)
M5 Y7 E63 K66 V67 H70 T73 D77 R97 Y99 T143 K146 W147 V152 Q155 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5yxu, PDBe:5yxu, PDBj:5yxu
PDBsum5yxu
PubMed
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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