Structure of PDB 5xpx Chain E Binding Site BS01

Receptor Information
>5xpx Chain E (length=381) Species: 1680634 (Pseudomonas sp. A3(2015c)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DAPIVLLHGFTGWGREEMFGFKYWGGVRGDIEQWLNDNGYRTYTLAVGPL
SSNWDRACEAYAQLVGGTVDYGAAHAAKHGHARFGRTYPGLLPELKRGGR
IHIIAHSQGGQTARMLVSLLENGSQEEREYAKAHNVSLSPLFEGGHHFVL
SVTTIATPHDGTTLVNMVDFTDRFFDLQKAVLEAAAVASNVPYTSQVYDF
KLDQWGLRRQPGESFDHYFERLKRSPVWTSTDTARYDLSVSGAEKLNQWV
QASPNTYYLSFSTERTYRGALTGNHYPELGMNAFSAVVCAPFLGSYRNPT
LGIDDRWLENDGIVNTVSMNGPKRGSSDRIVPYDGTLKKGVWNDMGTYNV
DHLEIIGVDPNPSFDIRAFYLRLAEQLASLR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5xpx Chain E Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5xpx Structure elucidation of truncated AMS3 lipase from an Antarctic Pseudomonas
Resolution2.77 Å
Binding residue
(original residue number in PDB)		D61 H81 H87 D238
Binding residue
(residue number reindexed from 1)		D55 H75 H81 D232
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.1.3: triacylglycerol lipase.
Gene Ontology
Molecular Function
GO:0004806 triacylglycerol lipase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:5xpx, PDBe:5xpx, PDBj:5xpx
PDBsum5xpx
PubMed
UniProtA0A0K0PTR1

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