Structure of PDB 5vco Chain E Binding Site BS01

Receptor Information
>5vco Chain E (length=222) Species: 6956 (Dermatophagoides pteronyssinus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TNACSINGNAPAEIDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAY
RNQSLDLAEQELVDCASQHGCHGDTIPRGIEYIQHNGVVQESYYRYVARE
QSCRRPNAQRFGISNYCQIYPPNANKIREALAQTHSAIAVIIGIKDLDAF
RHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNG
YGYFAANIDLMMIEEYPYVVIL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5vco Chain E Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5vco Structural Analysis of Der p 1-Antibody Complexes and Comparison with Complexes of Proteins or Peptides with Monoclonal Antibodies.
Resolution2.74 Å
Binding residue
(original residue number in PDB)		D56 L57 E59 E91
Binding residue
(residue number reindexed from 1)		D56 L57 E59 E91
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) Q28 C34 H170 N190
Catalytic site (residue number reindexed from 1) Q28 C34 H170 N190
Enzyme Commision number 3.4.22.65: peptidase 1 (mite).
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5vco, PDBe:5vco, PDBj:5vco
PDBsum5vco
PubMed26026055
UniProtP08176|PEPT1_DERPT Peptidase 1 (Gene Name=DERP1)

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