Structure of PDB 5ujt Chain E Binding Site BS01
Receptor Information
>5ujt Chain E (length=188) Species:
9606
(Homo sapiens) [
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SPEDFVYQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVTP
LGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRRVEPTVTIS
PSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGD
WTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRA
Ligand information
>5ujt Chain F (length=14) Species:
9606
(Homo sapiens) [
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VEELYLVAGEEGCG
Receptor-Ligand Complex Structure
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PDB
5ujt
C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Resolution
1.94 Å
Binding residue
(original residue number in PDB)
F11 G13 L26 Y30 Y37 A57 Y60 W61 E74 V78 H81 N82 L85
Binding residue
(residue number reindexed from 1)
F9 G11 L24 Y28 Y35 A55 Y58 W59 E72 V76 H79 N80 L83
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006955
immune response
GO:0019882
antigen processing and presentation
Cellular Component
GO:0016020
membrane
GO:0042613
MHC class II protein complex
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Biological Process
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Cellular Component
External links
PDB
RCSB:5ujt
,
PDBe:5ujt
,
PDBj:5ujt
PDBsum
5ujt
PubMed
29255035
UniProt
O19707
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