Structure of PDB 5sxu Chain E Binding Site BS01

Receptor Information
>5sxu Chain E (length=308) Species: 198628 (Dickeya dadantii 3937) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVE
NTQIERWINNGLWVPALEFINVVGSPDTGNKRLMLFPDGRVIYNARFLGS
FSNDMDFRLFPFDRQQFVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDE
WWIRGKASTHISDIRYDHLSSVQPNQNEFSRITVRIDAVRNPSYYLWSFI
LPLGLIIAASWSVFWLESFSERLQTSFTLMLTVVAYAFYTSNILPRLPYT
TVIDQMIIAGYGSIFAAILLIIFAHHRQANGVEDDLLIQRCRLAFPLGFL
AIGCVLVI
Ligand information
Ligand ID3CN
InChIInChI=1S/C3H9N/c1-2-3-4/h2-4H2,1H3
InChIKeyWGYKZJWCGVVSQN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04NCCC
CACTVS 3.341
OpenEye OEToolkits 1.5.0		CCCN
FormulaC3 H9 N
Name3-AMINOPROPANE
ChEMBLCHEMBL14409
DrugBank
ZINCZINC000016052656
PDB chain5sxu Chain E Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5sxu Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		F19 Y38 N103
Binding residue
(residue number reindexed from 1)		F10 Y29 N94
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
GO:0042802 identical protein binding
Biological Process
GO:0006811 monoatomic ion transport
GO:0007165 signal transduction
GO:0034220 monoatomic ion transmembrane transport
GO:0042391 regulation of membrane potential
Cellular Component
GO:0016020 membrane
GO:0043005 neuron projection

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5sxu, PDBe:5sxu, PDBj:5sxu
PDBsum5sxu
PubMed27916519
UniProtE0SJQ4

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