Structure of PDB 5oqd Chain E Binding Site BS01

Receptor Information
>5oqd Chain E (length=180) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKHRVNEEQIYCYCGKPGKFDHNMLQCCKCRNWFHTQCMQNFKKLLRGDM
FFVFCCTVCNNIEFVRRMQIEWVDVLHIALYNLRKHKYHHLLNDIWPFIL
EQRHQLPICLPETALMERLKQTLKDYSDRFVCGREFKRAPAFYALRHSGP
PHIPKVFLEPHEELSDELLEKRFKLMLMPE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5oqd Chain E Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5oqd DNA binding by PHF1 prolongs PRC2 residence time on chromatin and thereby promotes H3K27 methylation.
Resolution2.447 Å
Binding residue
(original residue number in PDB)		C515 C517 H538 C541
Binding residue
(residue number reindexed from 1)		C12 C14 H35 C38
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5oqd, PDBe:5oqd, PDBj:5oqd
PDBsum5oqd
PubMed29058710
UniProtQ24459|PCL_DROME Polycomb protein Pcl (Gene Name=Pcl)

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