Structure of PDB 5njk Chain E Binding Site BS01
Receptor Information
>5njk Chain E (length=133) Species:
9606
(Homo sapiens) [
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DEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKAVKA
VLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTT
RRWICHCFMAVKDTGERLSHAVGCAFAACLERK
Ligand information
>5njk Chain H (length=7) Species:
9606
(Homo sapiens) [
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AYIGPYL
Receptor-Ligand Complex Structure
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PDB
5njk
A Numb-Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer.
Resolution
3.13 Å
Binding residue
(original residue number in PDB)
R53 E112 K113 V114 S115 F116 C117 R132 W139 S155 H156 F162
Binding residue
(residue number reindexed from 1)
R26 E76 K77 V78 S79 F80 C81 R96 W103 S119 H120 F126
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5njk
,
PDBe:5njk
,
PDBj:5njk
PDBsum
5njk
PubMed
29269425
UniProt
P49757
|NUMB_HUMAN Protein numb homolog (Gene Name=NUMB)
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