Structure of PDB 5m0r Chain E Binding Site BS01

Receptor Information
>5m0r Chain E (length=257) Species: 36374 (Visna/maedi virus EV1 KV1772) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WIENIPLAEEEHNKWHQDAVSLHLEFGIPRTAAEDIVQQCDVCQIDHWQV
DYTHYEDKIILVWVETNSGLIYAERVKGETGQEFRVQTMKWYAMFAPKSL
QSDNGPAFVAESTQLLMKYLGIEHTTGIPWNPQSQALVERTHQTLKNTLE
KLIPMFNAFESALAGTLITLNIKRKGGLGTSPMDIFIFNKEQQRIQQQSK
SKQEKIRFCYYRTRKRGHPGEWQGPTQVLWGGDGAIVVKDRGTDRYLVIA
NKDVKFI
Ligand information
>5m0r Chain R (length=41) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caccggagcggatctcgcagtcgaccaccctaatcaagttt
Receptor-Ligand Complex Structure
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PDB5m0r A supramolecular assembly mediates lentiviral DNA integration.
Resolution8.2 Å
Binding residue
(original residue number in PDB)		H23 P29 R30 T31
Binding residue
(residue number reindexed from 1)		H23 P29 R30 T31
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.4: ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:5m0r, PDBe:5m0r, PDBj:5m0r
PDBsum5m0r
PubMed28059770
UniProtP35956|POL_VILVK Gag-Pol polyprotein (Gene Name=pol)

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