Structure of PDB 5ksu Chain E Binding Site BS01

Receptor Information
>5ksu Chain E (length=179) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTL
LGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTIS
PSNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVM
LEMTPQRGDVYTCHVEHPSLQSPITVEWR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ksu Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides.
Resolution2.73 Å
Binding residue
(original residue number in PDB)
F11 F47 Y60 W61 R77 V78 H81 N82 L85
Binding residue
(residue number reindexed from 1)
F9 F45 Y58 W59 R75 V76 H79 N80 L83
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process

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Cellular Component
External links
PDB RCSB:5ksu, PDBe:5ksu, PDBj:5ksu
PDBsum5ksu
PubMed28364043
UniProtQ5Y7D3

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