Structure of PDB 5k83 Chain E Binding Site BS01

Receptor Information
>5k83 Chain E (length=191) Species: 9544 (Macaca mulatta) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKPQIRNMVEPMDPRTFVSNFNNRPILSGLDTVWLCCEVKTKDPSGPPLD
AKIFQGKVYPKAKYHPEMRFLRWFHKWRQLHHDQEYKVTWYVSWSPCTRC
ANSVATFLAKDPKVTLTIFVARLYYFWKPDYQQALRILAEAGATMKIMNY
NEFQDCWNKFVDGRGKPFKPWNNLPKHYTLLQATLGELLRH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5k83 Crystal structures of APOBEC3G N-domain alone and its complex with DNA.
Resolution2.39 Å
Binding residue
(original residue number in PDB)
Y59 P60 K61 H65 W94 S95 Y124 Y125
Binding residue
(residue number reindexed from 1)
Y59 P60 K61 H65 W94 S95 Y124 Y125
Binding affinityPDBbind-CN: Kd=1.57uM
Enzymatic activity
Enzyme Commision number 3.5.4.-
3.5.4.38: single-stranded DNA cytosine deaminase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:5k83, PDBe:5k83, PDBj:5k83
PDBsum5k83
PubMed27480941
UniProtM1GSK9

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