Structure of PDB 5j0n Chain E Binding Site BS01

Receptor Information
>5j0n Chain E (length=274) Species: 10710 (Lambdavirus lambda) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSVTLHSWLDRYEKILASRGIKQKTLINYMSKIKAIRRGLPDAPLEDITT
KEIAAMLNGYIDEGKAASAKLIRSTLSDAFREAIAEGHITTNHVAATRAA
KSEVRRSRLTADEYLKIYQAAESSPCWLRLAMELAVVTGQRVGDLCEMKW
SDIVDGYLYVEQSKTGVKIAIPTALHIDALGISMKETLDKCKEILGGETI
IASTRREPLSSGTVSRYFMRARKASGLSFEGDPPTFHELRSLSARLYEKQ
ISDKFAQHLLGHKSDTEWDKIEIK
Ligand information
>5j0n Chain A (length=197) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gtcggcatagtgactgcatatgttgtgttttacagtattatgtagtctgt
tttttatgcaaaatctaatttaatatattgatatttatatcattttacgt
ttctcgttcagctttaatacaataagttggaattctaaaaaagcattgct
tatcaatttgttgcaacgaacaggtcactatcagtcaaaatattgat
Receptor-Ligand Complex Structure
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PDB5j0n Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction.
Resolution11.0 Å
Binding residue
(original residue number in PDB)		K136 S139 V175 R176 R177 K235 S281 Y288 H333
Binding residue
(residue number reindexed from 1)		K65 S68 V104 R105 R106 K164 S210 Y217 H262
Enzymatic activity
Enzyme Commision number 2.7.7.-
3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008907 integrase activity
GO:0016740 transferase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration
GO:0032359 provirus excision
GO:0044826 viral genome integration into host DNA
GO:0046718 symbiont entry into host cell
GO:0075713 establishment of integrated proviral latency

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Molecular Function
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Biological Process
External links
PDB RCSB:5j0n, PDBe:5j0n, PDBj:5j0n
PDBsum5j0n
PubMed27223329
UniProtP03700|VINT_LAMBD Integrase (Gene Name=int)

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