Structure of PDB 5fvc Chain E Binding Site BS01

Receptor Information
>5fvc Chain E (length=364) Species: 162145 (human metapneumovirus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLQGIHLSDLSYKHAILKESQYTIKRDVGTTTAVTPSSLQQEITLLCGEI
LYAKHADYKYAAEIGIQYISTALGSERVQQILRNSGSEVQVVLTRTLDIH
GVEKSWVEEIDKEARKTMATLLKESSGNIPQNQRPSAPDTPIILLCVGAL
IFTKLASTIEVGLETTVRRANRVLSDALKRYPRMDIPKIARSFYDLFEQK
VYHRSLFIEYGKALGSSSTGSKAESLFVNIFMQAYGAGQTMLRWGVIARS
SNNIMLGHVSVQAELKQVTEVYDLVREMGPESGLLHLRQSPKAGLLSLAN
CPNFASVVLGNASGLGIIGMYRGRVPNTELFSAAESYAKSLKESNKINFS
SLGLTDEEKEAAEH
Ligand information
>5fvc Chain K (length=70) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cccccccccccccccccccccccccccccccccccccccccccccccccc
cccccccccccccccccccc
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Receptor-Ligand Complex Structure
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PDB5fvc Nucleocapsid assembly in pneumoviruses is regulated by conformational switching of the N protein.
Resolution4.17 Å
Binding residue
(original residue number in PDB)		K171 S174 R185 R186 R189 V190 L243 N246 Q250 G255 T257 W261 M337 Y338 G340 R341
Binding residue
(residue number reindexed from 1)		K154 S157 R168 R169 R172 V173 L226 N229 Q233 G238 T240 W244 M320 Y321 G323 R324
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:5fvc, PDBe:5fvc, PDBj:5fvc
PDBsum5fvc
PubMed26880565
UniProtQ91F57

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