Structure of PDB 5ejk Chain E Binding Site BS01

Receptor Information
>5ejk Chain E (length=269) Species: 11888 (Rous sarcoma virus - Prague C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLREAKDLHTALHIGPRALSKASNISMQQAREVVQTCPHCNSAPALEAGV
NPRGLGPLQIWQTDFTLEPRMAPRSWLAVTVDTASSAIVVTQHGRVTSVA
VQHHWATAIAVMGRPKAIKTDNGSCFTSKSTREWMARWGIAHTTGIPGNS
QGQAMVERANRMMKDKIRVLAEGDGFMKRIPTSKQGEMMAKAMYALNHFE
RGENTKTPIQKHWRPTVLTEGPPVKIRIETGEWEKGWNVLVWGRGYAAVK
NRDTDKVIWVPSRKVKPDI
Ligand information
>5ejk Chain I (length=42) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gagtattgcataagacaacagtgcacgaaagaagaagacact
Receptor-Ligand Complex Structure
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PDB5ejk Crystal structure of the Rous sarcoma virus intasome.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		T66 W76 S150 E157 K164
Binding residue
(residue number reindexed from 1)		T66 W76 S150 E157 K164
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:5ejk, PDBe:5ejk, PDBj:5ejk
PDBsum5ejk
PubMed26887497
UniProtP03354|POL_RSVP Gag-Pol polyprotein (Gene Name=gag-pol)

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