Structure of PDB 5c6h Chain E Binding Site BS01

Receptor Information
>5c6h Chain E (length=154) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGV
QRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISF
GAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFH
VEDL
Ligand information
>5c6h Chain F (length=26) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PGVMTQEVGQLLQDMGDDVYQQYRSL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5c6h Structure of Mcl-1 complexed with Mule at 2.05 Angstroms resolution
Resolution2.05 Å
Binding residue
(original residue number in PDB)		F228 M231 K234 L235 R248 V249 H252 V253 D256 N260 G262 R263 T266 F318 F319
Binding residue
(residue number reindexed from 1)		F58 M61 K64 L65 R78 V79 H82 V83 D86 N90 G92 R93 T96 F148 F149
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

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Biological Process
External links
PDB RCSB:5c6h, PDBe:5c6h, PDBj:5c6h
PDBsum5c6h
PubMed
UniProtQ07820|MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (Gene Name=MCL1)

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