Structure of PDB 5c0a Chain E Binding Site BS01

Receptor Information
>5c0a Chain E (length=246) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DAGVIQSPRHEVTEMGQQVTLRCKPISGHDYLFWYRQTMMRGLELLIYFN
NNVPIDDSGMPEDRFSAKMPNASFSTLKIQPSEPRDSAVYFCASSLWEKL
AKNIQYFGAGTRLSVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLAT
GFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSA
TFWQDPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5c0a Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
Resolution2.46 Å
Binding residue
(original residue number in PDB)
D30 Y31 N51 W97
Binding residue
(residue number reindexed from 1)
D30 Y31 N51 W97
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5c0a, PDBe:5c0a, PDBj:5c0a
PDBsum5c0a
PubMed27183389
UniProtA0A0B4J2E0;
A0A5B9|TRBC2_HUMAN T cell receptor beta constant 2 (Gene Name=TRBC2)

[Back to BioLiP]