Structure of PDB 5bs0 Chain E Binding Site BS01
Receptor Information
>5bs0 Chain E (length=241) Species:
9606
(Homo sapiens) [
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AGVTQTPRYLIKTRGQQVTLSCSPISGHRSVSWYQQTPGQGLQFLFEYFS
ETQRNKGNFPGRFSGRQFSNSRSEMNVSTLELGDSALYLCASSFNMATGQ
YFGPGTRLTVTEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPD
HVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQD
PRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD
Ligand information
>5bs0 Chain C (length=9) Species:
9606
(Homo sapiens) [
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ESDPIVAQY
Receptor-Ligand Complex Structure
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PDB
5bs0
Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
F51 N97
Binding residue
(residue number reindexed from 1)
F49 N95
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5bs0
,
PDBe:5bs0
,
PDBj:5bs0
PDBsum
5bs0
PubMed
26758806
UniProt
A0A578
;
A0A5B9
|TRBC2_HUMAN T cell receptor beta constant 2 (Gene Name=TRBC2)
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