Structure of PDB 5ay8 Chain E Binding Site BS01

Receptor Information
>5ay8 Chain E (length=96) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRYKPGTLALREIRKYQKSTQLLLRKLPFQRLVREIAQAISPDLRFQSA
AIGALQEASEAYLVQLFEDTNLCAIHARRVTIMPRDMQLARRLRRE
Ligand information
>5ay8 Chain I (length=145) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcaatatccacctgcagattctaccaaaagtgtatttggaaactgctcc
atcaaaaggcatgttcagctgaattcagctgaacatgccttttgatggag
cagtttccaaatacacttttggtagaatctgcaggtggatattga
Receptor-Ligand Complex Structure
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PDB5ay8 Structure and function of human histone H3.Y nucleosome
Resolution2.8 Å
Binding residue
(original residue number in PDB)		R40 Y41 P43 G44 L46 A47 R49 R63 L65 R69 R83
Binding residue
(residue number reindexed from 1)		R3 Y4 P6 G7 L9 A10 R12 R26 L28 R32 R46
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:5ay8, PDBe:5ay8, PDBj:5ay8
PDBsum5ay8
PubMed27016736
UniProtP0DPK2|H3Y1_HUMAN Histone H3.Y (Gene Name=H3Y1)

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