Structure of PDB 4xxd Chain E Binding Site BS01
Receptor Information
>4xxd Chain E (length=206) Species:
9606
(Homo sapiens) [
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VQLVESGGGLVQPGGSLRLSCAASGFTFSRYSMSWVRQAPGKGLELVAQI
NSVGSSTYYPDTVKGRFTISRDNAKNTLYLQMNSLRAEDTAVYYCASGDY
WGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGA
LTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVD
KKVEPK
Ligand information
>4xxd Chain F (length=9) Species:
9606
(Homo sapiens) [
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KLVFFAEDV
Receptor-Ligand Complex Structure
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PDB
4xxd
Molecular basis for mid-region amyloid-beta capture by leading Alzheimer's disease immunotherapies.
Resolution
2.41 Å
Binding residue
(original residue number in PDB)
F27 Y32 S33 S94 G95 D96
Binding residue
(residue number reindexed from 1)
F26 Y31 S32 S97 G98 D99
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4xxd
,
PDBe:4xxd
,
PDBj:4xxd
PDBsum
4xxd
PubMed
25880481
UniProt
P01857
|IGHG1_HUMAN Immunoglobulin heavy constant gamma 1 (Gene Name=IGHG1)
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