Structure of PDB 4tsz Chain E Binding Site BS01

Receptor Information
>4tsz Chain E (length=363) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMHFTIQREALLKPLQLVAGVVEQTLPVLSNVLLVVEGQQLSLTGTDLEV
ELVGRVVLEDAAEPGEITVPARKLMDICKSLPNDVLIDIRVEEQKLLVKA
GRSRFTLSTLPANDFPEGPGSLNFSIAQSKLRRLIDRTSFAMAQQDVRYY
LNGMLLEVNGGTLRSVATDGHRLAMCSLDAQIPSQDRHQVIVPRKGILEL
ARLLTEQDGEVGIVLGQHHIRATTGEFTFTSKLVDGKFPDYERVLPRGGD
KLVVGDRQQLREAFSRTAILSNEKYRGIRLQLSNGLLKIQANNPEQEEAE
EEVQVEYNGGNLEIGFNVSYLLDVLGVIGTEQVRFILSDSNSSALVHEAD
NDDSAYVVMPMRL
Ligand information
Receptor-Ligand Complex Structure
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PDB4tsz Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		T172 G174 H175 P243 Y245 V248 Y324 N345 M363 P364 M365 R366
Binding residue
(residue number reindexed from 1)		T168 G170 H171 P239 Y241 V244 Y320 N341 M359 P360 M361 R362
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006260 DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0009360 DNA polymerase III complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4tsz, PDBe:4tsz, PDBj:4tsz
PDBsum4tsz
PubMed25170813
UniProtQ9I7C4|DPO3B_PSEAE Beta sliding clamp (Gene Name=dnaN)

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