Structure of PDB 4r8p Chain E Binding Site BS01

Receptor Information
>4r8p Chain E (length=97) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
Ligand information
>4r8p Chain I (length=144) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgagaatcccggtgccgaggccgctcaattggtcgtagacagctctagca
ccgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaagggg
attactccctagtctccaggcacgtgtcagatatatacatccga
Receptor-Ligand Complex Structure
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PDB4r8p Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome.
Resolution3.2846 Å
Binding residue
(original residue number in PDB)
H39 R40 Y41 P43 G44 V46 A47 R49 K56 R63 K64 L65 P66 R69 R83
Binding residue
(residue number reindexed from 1)
H2 R3 Y4 P6 G7 V9 A10 R12 K19 R26 K27 L28 P29 R32 R46
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:4r8p, PDBe:4r8p, PDBj:4r8p
PDBsum4r8p
PubMed25355358
UniProtP84233|H32_XENLA Histone H3.2

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