Structure of PDB 4qmg Chain E Binding Site BS01

Receptor Information
>4qmg Chain E (length=309) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAAT
QPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGK
DTNGENIAESLVAEGLATRRNNPEQNRLSECEEQAKAAKKGMWSEGNGSH
TIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTV
MLSGIKCPTFRRGSETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNIL
GTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLR
IWRDYVAPT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4qmg Structural Insights into the Tumor-Promoting Function of the MTDH-SND1 Complex.
Resolution2.701 Å
Binding residue
(original residue number in PDB)		P39 G41 G42 P43 R87 K88 I91 K93 F244 A246 F250 F251 S254 R255 R259 D260 H279 N281 E291 R324 R327
Binding residue
(residue number reindexed from 1)		P23 G25 G26 P27 R71 K72 I75 K77 F220 A222 F226 F227 S230 R231 R235 D236 H255 N257 E267 R300 R303
Enzymatic activity
Enzyme Commision number 3.1.31.1: micrococcal nuclease.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity

View graph for
Molecular Function
External links
PDB RCSB:4qmg, PDBe:4qmg, PDBj:4qmg
PDBsum4qmg
PubMed25242325
UniProtQ7KZF4|SND1_HUMAN Staphylococcal nuclease domain-containing protein 1 (Gene Name=SND1)

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