Structure of PDB 4p3w Chain E Binding Site BS01

Receptor Information
>4p3w Chain E (length=172) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAE
MGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVP
AEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYE
VSVKFNEEHIPDSPFVVPVASP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4p3w Crystal structure of the human filamin A Ig-like domains 20-21 in complex with migfilin peptide
Resolution2.0 Å
Binding residue
(original residue number in PDB)		M2207 G2208 T2263 R2264 A2268 G2269 G2270 L2271 A2272 I2273 A2274 V2275 E2276 G2277 P2278 S2279 K2280 A2281 I2283 F2285 E2301
Binding residue
(residue number reindexed from 1)		M51 G52 T107 R108 A112 G113 G114 L115 A116 I117 A118 V119 E120 G121 P122 S123 K124 A125 I127 F129 E145
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0051015 actin filament binding
Biological Process
GO:0030036 actin cytoskeleton organization

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Molecular Function
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Biological Process
External links
PDB RCSB:4p3w, PDBe:4p3w, PDBj:4p3w
PDBsum4p3w
PubMed
UniProtP21333|FLNA_HUMAN Filamin-A (Gene Name=FLNA)

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