Structure of PDB 4ol8 Chain E Binding Site BS01

Receptor Information
>4ol8 Chain E (length=381) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVWLQQKYREIIRNDLPPRPVKHDIEIKPGARLPRLQPYHVTEKNEQEIN
KIVQKLLDNKFIVPSKSPCSSPVVLVPGTFRLCVDYRTLNKATISDPFPL
PRIDNLLSRIGNAQIFTTLDLHSGYHQIPMEPKDRYKTAFVTPSGKYEYT
VMPFGLVNAPSTFARYMADTFRDLRFVNVYLDDILIFSESPEEHWKHLDT
VLERLKNENLIVKKKKCKFASEETEFLGYSIGIQKIAPHKCAAIRDFPTP
KTVKQAQRFLGMINYYRRFIPNCSKIAQPITEKQDKAIDKLKSPVLVPFN
YRLTTDASKDGIGAVLEVGYFSKSLESAQGELELLGIIKALHHFRYMLHG
KHFTLRTNHIEPARRVQRWLDDLATYDFTLE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4ol8 Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
C114 D116 R118 N121 L131 F185 G186 L187 V188 P191 N297
Binding residue
(residue number reindexed from 1)
C83 D85 R87 N90 L100 F154 G155 L156 V157 P160 N264
Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.26.4: ribonuclease H.
3.4.23.-
External links
PDB RCSB:4ol8, PDBe:4ol8, PDBj:4ol8
PDBsum4ol8
PubMed24608367
UniProtQ99315|YG31B_YEAST Transposon Ty3-G Gag-Pol polyprotein (Gene Name=TY3B-G)

[Back to BioLiP]