Structure of PDB 4nl8 Chain E Binding Site BS01

Receptor Information
>4nl8 Chain E (length=571) Species: 272620 (Klebsiella pneumoniae subsp. pneumoniae MGH 78578) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VAHVALPVPLPRTFDYLLPEAGCRVRVPFGKQERIGIVKPVLDDEPVFST
TVWRLLMWAAEYYHHPIGDVLFHALPVMLRQGKPASALRLNTEQATAVGA
IHSAADRFSAWLLAGITGSGKTEVYLSVLENVLAQGRQALVMVPEIGLTP
QTIARFRQRFNAPVEVLHSGLNDSERLSAWLKAKNGEAAIVIGTRSSLFT
PFKDLGVIVIDEEHDSSYKQQEGWRYHARDLAVWRAHSEQIPIILGSATP
ALETLHNVRQGKYRQLTLSPAQQHVLDLKGQPLQAGLSPALISRMRQHLQ
ADNQVILFLNRRGFAPALLCHDCGWIAECPRCDSYYTLHQAQHHLRCHHC
DSQRPIPRQCPSCGSTHLVPVGIGTEQLEQALAPLFPEVPISLAAVHRGG
ARILIGTQMLAKGHHFPDVTLVSLLDVDGALFSADFRSAERFAQLYTQVS
GRQGEVILQTHHPEHPLLQTLLYKGYDAFAEQALAERQTMQLPPWTSHVL
IRNQQAPLFLQQLRNLLQASPLADEKLWVLGPVPALAWQILLQHPSRVRL
QHIVSGTLALIWVLDVDPIEG
Ligand information
>4nl8 Chain F (length=3) Species: 1125630 (Klebsiella pneumoniae subsp. pneumoniae HS11286) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
IPF
Receptor-Ligand Complex Structure
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PDB4nl8 Structural mechanisms of PriA-mediated DNA replication restart.
Resolution4.08 Å
Binding residue
(original residue number in PDB)		R697 V698
Binding residue
(residue number reindexed from 1)		R547 V548
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0043138 3'-5' DNA helicase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0006270 DNA replication initiation
GO:0006302 double-strand break repair
GO:0006310 DNA recombination
GO:0032508 DNA duplex unwinding
Cellular Component
GO:1990077 primosome complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4nl8, PDBe:4nl8, PDBj:4nl8
PDBsum4nl8
PubMed24379377
UniProtA6TGC5

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