Structure of PDB 4ji6 Chain E Binding Site BS01

Receptor Information
>4ji6 Chain E (length=150) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLA
VQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGA
VPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG
Ligand information
>4ji6 Chain A (length=1514) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaag
acaugcaagucgugcgggccgcgggguuuuacuccguggucagcggcgga
cgggugaguaacgcgugggugaccuacccggaagagggggacaacccggg
gaaacucgggcuaaucccccauguggacccgccccuugggguguguccaa
agggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguuggug
ggguaauggcccaccaaggcgacgacggguagccggucugagaggauggc
cggccacaggggcacugagacacgggccccacuccuacgggaggcagcag
uuaggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuugg
aggaagaagcccuucgggguguaaacuccugaacccgggacgaaaccccc
gacgaggggacugacgguaccgggguaauagcgccggccaacuccgugcc
agcagccgcgguaauacggagggcgcgagcguuacccggauucacugggc
guaaagggcguguaggcggccuggggcgucccaugugaaagaccacggcu
caaccgugggggagcgugggauacgcucaggcuagacggugggagagggu
gguggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgc
cgauggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaag
cguggggagcaaaccggauuagauacccggguaguccacgcccuaaacga
ugcgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagc
gcgccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacg
ggggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaa
gaaccuuaccaggccuugacaugcuagggaacccgggugaaagccugggg
ugccccgcgaggggagcccuagcacaggugcugcauggccgucgucagcu
cgugccgugagguguuggguuaagucccgcaacgagcgcaacccccgccg
uuaguugccagcgguucggccgggcacucuaacgggacugcccgcgaaag
cgggaggaaggaggggacgacgucuggucagcauggcccuuacggccugg
gcgacacacgugcuacaaugcccacuacaaagcgaugccacccggcaacg
gggagcuaaucgcaaaaaggugggcccaguucggauuggggucugcaacc
cgaccccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcg
gugaauacguucccgggccuuguacacaccgcccgucacgccaugggagc
gggcucuacccgaagucgccgggagccuacgggcaggcgccgaggguagg
gcccgugacuggggcgaagucguaacaagguagcuguaccggaaggugcg
gcuggauccuuucu
......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<
<<.<<<..<<<..<<.<<<<<<<<<.......>>>>>>>>>.>>>>>...
...<<.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<.
.....>>>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>.
.<<<<...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<
<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...
>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>
>>>........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<
<<......<<<<....>>>>.....>>>>....<<<<<........<<<<
.....>>>>..........>>>>>......<<<<<(((...<<<<<....
.<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<
((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<..
...>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<
<<<....<<<<<<<.<..<<<......>>>.....>.>>>>>>>......
.....<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<
<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>.........
.<<<<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>
>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<
.<<<<<<<.<<.<<<<<<..<<<<<<<<.<......<<........>>..
........<<<<<<<.......<<<<<<...<<<<<<<....>>>>>>>.
.................>>>>>>..<<<.<<<..<<<<<<.......<<<
<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<
<<<<...<...<<<.....>>>>.....>>>>>>>.....<<<<<....>
>>>>........>>>>.........>>>...>>>>>>>>>...>>>>>>>
...>..>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>
>>..>>....>>>.....>>>>>>>......<....<<<<<<<.......
.>>>>>>>....>.....>>>>>>....<<<<<<<..........>>>>>
>>......>>...>>>>>>>>>>.>>.......<<.<.<<<<.<<<..<<
<<<<<<<<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>>>
>>>>>>..>>.>>>>>..>.>>.........<<<<<<<<<....>>>>>>
>>>...........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4ji6 The central role of protein S12 in organizing the structure of the decoding site of the ribosome.
Resolution3.55 Å
Binding residue
(original residue number in PDB)		R14 T16 A17 R18 M19 Q20 A21 G22 R25 R27 K47 K57 A86 K92 A94 A95 T98 I101 A102 L119 T120 K121 E122 S125 R126 N127 N130 Y133
Binding residue
(residue number reindexed from 1)		R10 T12 A13 R14 M15 Q16 A17 G18 R21 R23 K43 K53 A82 K88 A90 A91 T94 I97 A98 L115 T116 K117 E118 S121 R122 N123 N126 Y129
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4ji6, PDBe:4ji6, PDBj:4ji6
PDBsum4ji6
PubMed24152548
UniProtQ5SHQ5|RS5_THET8 Small ribosomal subunit protein uS5 (Gene Name=rpsE)

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